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A Case Report of Rifampicin Induced Thrombocytopenia

Jitendra A Sisodia, Shrikant Hiremath, KR Patel, and MM Patel.

Rifampicin is an important drug in the treatment of tuberculosis (mycobacterial disease) under RNTCP ( which is given intermittently according to weight). With clinical experience it has been shown that drug is well tolerated with minor side effects. But it can also cause some life threatening complications like hepatitis, hypersensitivity reaction leading to hemolysis, haemoglobinuria, hematuria, renal insufficiency and ARF, thrombocytopenia and bleeding disorder. These adverse effects are common with intermittent therapy than with daily regimen. We are reporting a case of rifampicin induced Acute thrombocytopenia in a patient who is on AKT CAT-I regimen under RNTCP