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Novel Zinc(II) Complexes with Thiadiazole Containing Schiff Bases: Syntheses and Structural Characterization

Naveen KRM, Shiva PK, Nayak S and Prasad N

Herein we describe the synthesis of three zinc(II) complexes of thiadiazole derived Schiff base ligand. All the reported complexes were characterized by analytical and spectroscopic techniques. The data obtained from the characterization techniques confirmed the structures of synthesized complexes. The antibacterial activity of the reported compounds were studied using E. coli, B. subtilis and S. aureus. The results obtained from antibacterial investigations revealed that the tested zinc(II) complexes showed potent microbial growth inhibition than their respective thiadiazole Schiff base ligands. The growth inhibition was compared with standard antibacterial drug Streptomycin.