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Microwave Energy: A Potential and Efficient Source of Energy in Pharmaceutical Chemistry

Reshma Rani*, Atul Kumar*

Biphenyl derivatives have been synthesized in very high yields by nucleophilic addition of various substituted boronic acids on iodine substituted methyl ester derivatives, which can be further used as starting material for bio-relevant organic molecules. Here, in this paper we report a novel, fast, eco-friendly synthesis of biphenyl aromatic compound via insertion of phenyl ring in moisture sensitive substrate by using palladium catalyst under microwave irradiation (MWI).